V8 Nexus technical specifications

V8 Nexus Key Features

• Cap piercing and sample agitation capabilities * New feature
• Rapid capillary technology (up to 96 tests per hour)
• Flexible wavelength detection capability for new and enhanced methods
• Connectivity to fully automated laboratory track systems
• Four independent buffer locations with automatic switching and full bar-coded traceability
• Continuous loading of sample tubes with 112-tube on-board capacity
• Flexible, peltier-cooled on-board reagents (6 positions) and diluent (4 positions) * New feature
• Automated gel tray preparation for Serum, Urine Protein, IFE and Haemoglobin tests * New feature
• Automated maintenance and scheduled start-up and shut-down settings * New feature

Methods and Analysis

• New, optimised Fast Serum Protein method designed specifically for V8 Nexus
• CZE (Capillary Zone Electrophoresis) and IEF (Isoelectric Focusing) techniques for optimum results
• Automated reflex testing to capillary immunodisplacement or to gel immunofixation
• Automated Haemoglobin A1c method
• Automated Haemoglobin UltraScreen CZE method * New test
• Carbohydrate Deficient Transferrin (CDT Auto) method
• Glyco Liver Profile * New test
• Carbamylated Albumin * New feature

Platinum 6 Key Features

• Revolutionary touch-screen interface with real-time system control and status monitoring * New feature
• Combine and view gel and capillary results from unlimited analysers * New feature
• Remote networked analysis and interpretation
• Unlimited database capacity (constrained only by storage hardware) * New feature
• Expert System automates the identification and approval of normal samples, and the re‑testing of abnormal samples
• Full auditable traceability, ISO 15189 ready

Analysis Hardware

• Eight-channel capillary electrophoresis
• New capillary technology for rapid serum protein analysis * New feature
• FlexWave variable-wavelength detection range of 200-600nm for novel methodologies including reflex testing for interfering factors, and screening for contrast media * New feature

Track Automation

• Connectivity to automated laboratory track systems:
• Inpeco FlexLab
• Abbott Accelerator
• Siemens Aptio (in development)

Sample Handling

• Continuous random access sample loading of up to 112 samples at a time
• Sample dead volume of 50µL  — sample tube dependent
• Positive patient identification with integrated barcode reader for full sample traceability

Gel Tray Sample Integration

• Can prepare SAS-1 and SAS-3 gel sample trays for the following applications:
• Serum Protein electrophoresis (up to 100 samples)
• Urine Protein electrophoresis (up to 100 samples)
• Immunofixation (up to 15 serum and urine samples)
• Alkaline haemoglobin (up to 40 samples) * New feature
• Acid haemoglobin (up to 12 samples) * New feature
• Automated pre-lysis for whole-blood haemoglobin samples * New feature
• Full audit trail and sample traceability — ISO 15189 ready

Smart System Features

• Fully automated maintenance procedures at start up, shut down and between procedures
• Scheduled start up and shut down maintenance procedures * New feature
• Service alert feature to ensure instruments are serviced when required * New feature
• Automated system check to monitor the performance of key parts * New feature

Buffer Handling

• Six on-board buffer locations
• Up to four simultaneously accessible assay buffers, and two rinse/utility buffers
• Load multiple methods at the same time
• All buffers are bar-coded for full audit traceability
• Buffer usage optimisation with not-in-use buffers no longer purged * New feature

Reagent Bay

• Ten on board reagent locations
• Four diluent reagent positions, enough for up to 668 tests * New feature
• Six open positions for antisera and reagents * New feature
• Peltier temperature controlled reagent bay for controlled stability and reduction in reagent loss

General Features

• Touch screen, intuitive, modern and powerful software interface * New feature
• Database capacity constrained only by storage hardware
• Unlimited storage capacity
• Network database functionality for storage of data on laboratory networks
• Remote viewing of data
• Customised gel and capillary method parameters
• Host query, bidirectional super fast TCP/IP LIMS/LIS connectivity
• Import 10 patient demographics 
• Import 12 patient chemistry analysis results
• Automated auto query/auto send
• Method host query

Analysis

• Customisable and configurable individual workspace for every user
• Customisable and configurable trace view, including:
• Peak name labelling
• Peak colouring
• Axis adjustment
• Overlay normal trace(s)
• Derivative view for small monoclonal proteins
• Automated linking of sample with historical data
• Historical view of previous patient results all on one screen * New feature
• Immunowindow view of immunodisplacement results for clear immunotype identification
• Full suite of touch-optimised editing tools, including:
• Gating of peaks
• Insertion of peaks
• Quantifying monoclonal bands
• Editing baseline
• Automated retrieval of samples for reflex testing

Instrument Diagnostics and Monitoring

• Advanced hardware feedback for real-time status updates * New feature
• Updates include:
• Full sample status and timing (from entering the instrument to completion of analysis) * New feature
• Full buffer and reagent volume monitoring 
• Electrophoresis status and timing monitoring * New feature
• Maintenance status and timing monitoring * New feature
• Service alert * New feature

Advanced Software Features

• User-friendly Expert System, offering automated flagging and clearing of abnormal results for reflex testing to immunotyping, with a straightforward user interface * New feature
• Instrument status monitoring with a comprehensive quality control (QC) package with the following features:
• Automated barcode input of QC sample ranges and data * New feature
• QC status icon * New feature
• QC alert when QC has expired or failed * New feature
• Levey Jennings chart and statistical reports to track QC performance * Updated feature
• Customisable Westgard rules for analysing QC results
• Intuitive commenting modules for easy and standardised reporting of results
• Customisable report module for hard copy reporting
• Customise templates or create reports from scratch

Methods

• Auto-reflex testing utilising user defined wavelengths * New feature
• Customisable immunofixation dilution factors * New feature
• Automated immunofixation dilution based on monoclonal/polyclonal size * New feature
• Pre-lysis of haemoglobin samples to further automate Hb analysis * New feature

V8 Nexus Standard Configuration:

V8 Nexus with Rapid SP Upgrade: