TubeSpin Bioreactors
TPP TubeSpin® Bioreactors have a proven track record in large scale screening and optimisation processes of suspension cells.
The optimisation of the parameters are important for production up-scaling and can be evaluated using small amounts of culture, therefore maximising the number of parallel experiments all at the same time.
Key features:
TubeSpin® Bioreactor 15:
- Working volume 1 – 15 ml
- Round form
- 5 openings (A, B, C, D, E) of different size above the gas permeable, sterile PTFE filter of the screw cap
- Openings can be sealed and by this, exchange adjusted to need
- Sterile gas exchange is guaranteed by the 0.22 µm filter membrane
- Even with a high cell density the supply of oxygen through the openings is sufficient
- Tube fits in a standard 15 ml centrifuge rotors
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TubeSpin® Bioreactor 50:
- Working volume 1 – 35 ml
- Conical bottom
- 5 openings (A, B, C, D, E) of different size above the gas permeable, sterile PTFE filter of the screw cap
- Openings can be individually sealed
- Sterile gas exchange is guaranteed by the 0.22 µm filter membrane
- Even with a high cell density the supply of oxygen through the openings is sufficient
- Tube fits in a standard 50 ml centrifuge rotor
TubeSpin® Bioreactor 600:
- Filling volume 600 ml, optimal working volume up to ca. 400 ml
- Optimizes production parameters
- Optimal supply of oxygen through the openings
- 10 openings in the screw cap above the gas permeable, sterile PTFE filter
- Tube fits many 1000 ml rotors
- Special racks for shakers available
- Rack for 3 x Bioreactor 600 or other large vessels available
Water loss
- If small culture volumes are incubated over a longer period of time, the loss of water influences the growth of cells.
- By the closure of one or several openings above the gas permeable and sterile PTFE membrane, this water loss can be minimized.
- Sterile gas exchange is guaranteed through the 0.22 µm pore size PTFE filter membrane.
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